The use of alcohol with prednisone usage has multiple reasons to avoid it. Depending upon what is the dose or nature of inflammation treated, prednisone by itself has numerous problems through out the body and mind that may cause damage or even psychosis. What is the result of interaction between prednisone and sun? Commonly, it is stated that we should not stay out in the sun while taking prednisone. While a drink or two might not have any impact on your health while you take prednisone, it’s always best to talk to your doctor first to avoid complications and give you the best outcome. “Can I take Zithromax and alcohol together?” One of the most common questions I get asked is whether it is OK to drink alcohol while on antibiotics. This question has also been asked and answered here: Can you drink alcohol while taking prednisone? Alcohol and medication can be a dangerous mix. Doctors recommend avoiding alcohol while taking many drugs. The biggest concern is that taking alcohol with medications might increase the risk of. Foods such as Junk food like chocolate or candy should be avoided. Any food in the cabbage family can cause your baby to have gas while breast feeding. Helpful, trusted answers from Doctors: Dr. Ein remarks on whether or not you can drink alcohol while taking levofloxacin. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Larson on can you drink alcohol while taking prednisone: Alcohol in modest amounts is not a significant issue. Maintain good hygiene habits. Taking prednisone decreases the body's immunity, making you more susceptible to infection and illnesses that you might not otherwise contract.